The latest NAION / Ozempic lawsuit update, MDL status, legal case updates, and litigation developments. This hub is updated to reflect current lawsuit news and legal developments.
Last updated: March 15, 2026
No. 3163 (E.D. Pa.)
Hon. Karen S. Marston
Growing (federal + state)
Discovery and bellwether planning ongoing
NAION / Ozempic lawsuit news continues to develop as the federal multidistrict litigation (MDL) in the Eastern District of Pennsylvania gets underway. Individual vision loss claims are coordinated there—not as a class action—allowing each plaintiff's case to be evaluated on its own merits while sharing common discovery and pretrial rulings.
NAION/GLP-1 litigation is centralized in In re: GLP-1 RA Products Liability Litigation (No. II), MDL No. 3163, in the Eastern District of Pennsylvania before Judge Karen S. Marston. The MDL was created in December 2025. This consolidation streamlines discovery, bellwether selection, and rulings on common legal and scientific issues. Plaintiffs allege that Novo Nordisk and Eli Lilly knew or should have known about the risk of NAION (vision loss) with Ozempic, Wegovy, Mounjaro, Zepbound, and related GLP-1 drugs and failed to adequately warn patients and doctors.
An MDL is different from a class action. In a class action, one outcome would apply to the whole group. In the MDL, each plaintiff keeps an individual case and any settlement or verdict is based on that person's injuries and damages. This structure typically allows for higher compensation for those with more severe harm.
| Date / Period | Development |
|---|---|
| July 2024 | JAMA Ophthalmology study finds significantly elevated NAION risk with semaglutide (4.28x–7.64x). |
| June 2025 | European Medicines Agency adds NAION as a "very rare" side effect for semaglutide-containing medicines. |
| December 2025 | Judicial Panel on Multidistrict Litigation creates MDL No. 3163 (E.D. Pa.) for GLP-1 NAION vision loss cases; Judge Karen S. Marston assigned. |
| 2026 | Discovery and bellwether planning ongoing. Additional cases filed in federal and state court. |
Peer-reviewed research has raised concerns about an association between GLP-1 receptor agonists (e.g., semaglutide) and NAION. Plaintiffs allege that manufacturers knew or should have known of this risk and failed to warn. Key developments include:
If you took Ozempic, Wegovy, or another GLP-1 drug and were diagnosed with NAION or sudden vision loss, you may be eligible for a free case review. Get the full picture on eligibility, settlement estimates, and how to get connected with a law firm.
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Start Free Case ReviewThis NAION / Ozempic lawsuit news page is for informational purposes only and does not constitute legal advice. Top Tier Legal LLC is not a law firm. Litigation status and dates may change. For the most current update and to see if you qualify for a free case review, visit our NAION & Ozempic lawsuit page or contact us.